Portland Trail Blazer vs Los Angeles Lakers regular season injury report: Who's playing, who's out, and more (October 27, 2025)

The regular season matchup between the Portland Trail Blazers and Los Angeles Lakers on October 27, 2025, at Crypto.com Arena arrives amid major injury woes for both teams. Despite the star power missing on both sides, this West Coast clash promises intensity, unpredictability, and plenty of opportunities for rising talents to shine.

Los Angeles Lakers’ Injury Report vs Portland Trail Blazers (October 27, 2025)

The Los Angeles Lakers enter this game with a lineup that barely resembles the one fans expected to see at the start of the season. The biggest blow is the loss of Luka Doncic, who has been sidelined with both a left finger sprain and a lower left leg contusion. Doncic’s absence comes just as he was finding his rhythm in Los Angeles - scoring a combined 92 points in his first two games before the injuries struck. He’s expected to miss at least a week of action.Meanwhile, LeBron James remains out as he deals with a lingering sciatic nerve issue. The 40-year-old superstar, who continues to defy age and expectations, is projected to return sometime around mid-November.

Unfortunately for the Lakers, the list doesn’t end there. Adou Thiero (knee) and Maxi Kleber (oblique) have both been ruled out, limiting LA’s options on the perimeter and inside the paint. Jaxson Hayes (knee) and Gabe Vincent (ankle sprain) are listed as questionable, each having missed recent games or exited early due to recurring pain.

With several key players unavailable, the Lakers are expected to lean heavily on Austin Reaves, who’s coming off a red-hot performance with 51 points, 11 rebounds, and 9 assists in his last game. Rui Hachimura is likely to take on a larger scoring role, while Marcus Smart will be tasked with leading the offense as the primary playmaker.

Portland Trail Blazers’ Injury Report vs Los Angeles Lakers (October 27, 2025)

The Portland Trail Blazers, though brimming with young potential, are dealing with their own set of significant absences.

Damian Lillard - the heart and soul of the franchise - will miss the entire 2025–26 season after suffering a devastating Achilles injury during preseason media days. His absence has forced head coach Chauncey Billups to experiment with creative rotations.Last year’s top rookie, Scoot Henderson, is also unavailable due to a hamstring tear that could keep him sidelined until at least mid-November. Robert Williams III remains out as well, still undergoing reconditioning after persistent knee problems.With so many of their core players missing, the Blazers are turning to a younger rotation anchored by Jrue Holiday, Shaedon Sharpe, and Deni Avdija. Jerami Grant’s veteran experience and Toumani Camara’s high-energy play are expected to be vital in keeping the team competitive.

Portland Trail Blazers vs Los Angeles Lakers: Who Steps Up?

Both squads are missing their biggest names, which makes this matchup an open canvas for unexpected performances. For the Lakers, Austin Reaves and Rui Hachimura will be under the spotlight to sustain offensive production, while Smart’s leadership could determine how smoothly LA’s offense functions without its stars.For Portland, Jrue Holiday’s two-way excellence will be central to their game plan. Sharpe’s athleticism and confidence could be the X-factor, while Grant and Camara are expected to bring stability and hustle on both ends.While the marquee names are missing, this game has the potential to be a high-energy showdown between hungry young players eager to prove their worth. Both teams will need to dig deep into their benches, rely on role players, and embrace a gritty style of play.

Expect defensive intensity, long scoring droughts, and possibly one or two breakout performances that could steal the spotlight.

Portland Trail Blazers vs Los Angeles Lakers Complete Injury Report (October 27, 2025)

How to Watch Portland Trail Blazers vs Los Angeles Lakers (October 27, 2025)

• Tip-Off: 10:30 p.m. ET / 7:30 p.m. PT• TV: KUNP and SportsNet LA• Streaming: FuboTV, NBA League Pass (regional restrictions may apply)Also read: Is LeBron James playing tonight vs Portland Trail Blazers? Latest update on the Los Angeles Lakers star's injury report (October 27, 2025)Both the Lakers and Trail Blazers are entering this contest with depleted rosters and uncertain rotations, yet that’s what makes this matchup so intriguing. Without the usual star power, it’s a battle of adaptability and depth - an opportunity for emerging players to seize the moment. For fans craving a scrappy, unpredictable NBA contest filled with hustle, heart, and surprises, this game at Crypto.com Arena is one to watch.