Detroit Pistons vs Boston Celtics regular season game: Full injury report, who's out, and more (December 15, 2025)

The Detroit Pistons arrive in Boston carrying momentum, confidence, and one of the league’s best early-season records. At 20–5 and winners of three straight, Detroit heads into TD Garden on December 15, 2025, to face a Celtics team still trying to find consistency amid injuries.

Boston sits at 15–10, solid at home but clearly shorthanded, setting the stage for a matchup where availability may matter as much as execution.Oddsmakers expect a tight contest. Detroit opens as a slight +1.5 underdog on the road, while the total hovers between 229.5 and 231.5 points, reflecting expectations of a fast-paced, offense-driven night. With both teams capable of scoring in bunches and defensive rotations already stressed, this game carries the feel of an early-season playoff test.

Detroit Pistons and Boston Celtics Injury Report (December 15, 2025)

As of the December 14 NBA injury report, both teams were listed as “NOT YET SUBMITTED,” making last-minute updates crucial before the 7:00 PM ET tip-off. Detroit Pistons’ most notable concern is forward Isaac Jones, dealing with a left knee sprain that leaves him out or questionable. If cleared, a G League assignment could still be in play. Bobi Klintman remains sidelined with an ankle injury, thinning Detroit’s frontcourt depth.

Boston Celtics’ situation is more defined but equally impactful. Jayson Tatum continues to miss time after last season’s Achilles injury, forcing the Celtics to reshape their offense nightly. Ron Harper Jr. is out or questionable due to knee concerns or two-way availability, while Chris Boucher is battling illness and remains questionable.

How the Absences Shape the Game

Without Tatum, Boston Celtics lean heavily on Jaylen Brown, who has carried the scoring load at 30 points per game, supported by Derrick White’s all-around impact on both ends.

In the paint, Neemias Queta has stepped into a larger role, averaging double-digit points and rebounds while anchoring the interior.Detroit Pistons counter with balance. Cade Cunningham continues to orchestrate the offense with nearly nine assists per game, while Jalen Duren controls the glass. Ausar Thompson’s defensive versatility and energy remain key, especially if the Pistons’ frontcourt rotation is shortened.

The bench battle could be decisive, particularly if Boston’s shooters exploit Detroit’s perimeter gaps.

Detroit Pistons vs Boston Celtics Projected Starting Lineups (December 15, 2025)

Boston Celtics are expected to roll out Jordan Walsh, Jaylen Brown, Neemias Queta, Payton Pritchard, and Derrick White, emphasizing spacing and defensive flexibility. Detroit’s projected five features Tobias Harris, Ausar Thompson, Jalen Duren, Duncan Robinson, and Cade Cunningham, with playmaking and ball movement at the core.Also read: Is Jayson Tatum playing tonight vs the Detroit Pistons? Latest update on the Boston Celtics star's injury report (December 15, 2025)

Detroit Pistons and Boston Celtics Stakes and Betting Outlook (December 15, 2025)

Detroit’s 80% win rate, including an impressive 8–3 road mark, collides with Boston’s strong home form at TD Garden. Bettors are eyeing the over given both teams’ scoring trends, but injuries inject volatility into every possession. Cunningham versus White, and Duren battling Queta inside, could ultimately decide whether this night belongs to the surging Pistons or the resilient Celtics.